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Time Table of Lyme Disease
|
|
1975 |
First Lyme Disease case reported (Lyme,
Connecticut) |
|
1981 |
Microbe identified |
|
1989 |
OspA (an outer surface protein) found and cloned |
|
early 1990s |
OspA antibodies found in many patients with
chronic Lyme disease |
|
1990-92 |
Vaccinations with rOspA found to protect mice
against Lyme disease infections |
|
1992-95 |
Vaccinations with rOspA tested in other animals |
|
1995 |
Lyme vaccine found safe and effective in persons
with Lyme disease |
|
1995-98 |
Vaccine found safe and effective in people
without Lyme disease |
|
1998 |
FDA approved Lyme vaccine |
|
2002 |
Manufacturer pulls vaccine from the market |
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adapted from NIAID Lyme Disease website
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