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Institute for Vaccine Safety

Johns Hopkins Bloomberg School of Public Health

615 N. Wolfe Street

Room W5041

Baltimore, MD 21205

www.vaccinesafety.edu

 

 

Allergens per 0.5 mL 

Excipients Table
Components Table

 

Amphotericin B

RabAvert (Novartis)

Rabies

< 2 ng

Chlortetracyclin

RabAvert (Novartis)

Rabies

1 mcg

Egg

Afluria (CSL)

Influenza

≤1 mcg

 

Agriflu (Novartis)

Influenza

<0.4 mcg

 

Fluarix (GSK)

Influenza

≤0.05 mcg

 

FluLaval (GSK)

Influenza

residual (≤1 mcg ovalbumin)

 

Flumist (MedImmune)

Influenza

residual

 

Fluvirin (Novartis)

Influenza

residual (≤1 mcg ovalbumin)

 

Fluzone (sp)

Influenza

residual

 

MMR II (Merck)

MMR

residual

 

ProQuad (Merck)

MMR+varicella

residual

 

RabAvert (Chiron)

Rabies

<3 ng/dose

Gelatin (Bovine)

RabAvert (Novartis)

Rabies

<12 mg (Polygeline)

Gelatin (Porcine)

Flumist (MedImmune)

Influenza

Hydrolyzed Gelatin, 2.00 mg

 [click here for information from religious leaders on on use of these vaccines] 

Fluzone (sp)

Influenza

0.05% in 0.25 mL and 0.5 mL dose

JE-Vax

Japanese Encephalitis

500 mcg (per 1 mL dose)

MMR II (Merck)

MMR

Hydrolyzed Gelatin, 14.5 mg

 

ProQuad (Merck)

MMR+varicella

Hydrolyzed Gelatin, 11 mg

 

Tripedia (sp)

DTaP

residual used in the production of the pertussis concentrate

 

Varivax (Merck)

Varicella

Hydrolyzed Gelatin, 12.5 mg

 

YF-Vax (sp)

Yellow Fever

as stabilizer

 

Zostavax (Merck)

Varicella Zoster

Hydrolyzed gelatin, 15.58 mg

Gentamicin Sulfate

Flumist (MedImmune)

Influenza

<0.015 mcg/mL

 

Fluarix (GSK)

Influenza

≤0.15 mcg

Latex

ActHIB (AP)

Hib

Diluent vial stopper; vaccine vial contains no rubber

Agriflu (Novartis)

Influenza

Prefilled syringe tip may contain latex

Biothrax (Emergent)

Anthrax

Vial stopper contains lates

 

Boostrix (GSK)

Tdap

Cap/Plunger of needleless prefilled syringe contains dry natural latex rubber

 

Certarix (GSK)

HPV

Tip cap and plunger of needleless prefilled syringes contain dry natural latex rubber

 

Comvax (Merck)

Hib-HepB

Stopper

 

DAPTACEL (sp)

DTaP

Stopper

 

DT (AP)

DT

Stopper

 

Engerix-B (GSK)

Hep B

Cap/Plunger of needleless prefilled syringe contain dry natural latex rubber

 

Fluarix (GSK)

Influenza

Cap/Plunger of needleless prefilled syringe contain dry natural latex rubber

 

Fluvirin (Novartis)

Influenza

Prefilled syringes may contain latex

 

Fluzone (sp)

Influenza

Prefilled syringes may contain latex

 

Havrix (GSK)

Hep A

Cap/Plunger of needleless prefilled syringe contain dry natural latex rubber

Hiberix (GSK)

Hib

Prefilled syringes may contain latex

 

Infanrix (GSK)

DTaP

Cap/Plunger of needleless prefilled syringe contain dry natural latex rubber

 

Kinrix (GSK)

DTaP/IPV

Syringe may contain dry natural latex rubber

 

Menactra (sp)

Meningococcal

Stopper

 

MENOMUNE (sp)

Meningococcal

Stopper

 

Pediarix (GSK)

DTaP-HepB-IPV

Cap/Plunger of needleless prefilled Syringe contain dry natural latex rubber

 

PedvaxHIB (Merck)

Hib

 

 

Rotarix (GSK)

Rotaviris

Tip cap and Rubber Plunger of applicator

 

TriHIBit (sp)

DTaP-Hib

Diluent vial stopper; vaccine vial contains no rubber

 

Tripedia (sp)

DTaP

Stopper

 

Twinrix (GSK)

Hep AB

Tip cap and plunger of needleless prefilled syringes contain dry natural latex rubber; vial stopper is latex-free

 

Vaqta (Merck)

Hepatitis A

Stopper

 

YF-Vax (sp)

Yellow Fever

Stopper

Neomycin

ACAM2000 (sp)

Smallpox

trace amounts

 

Afluria (CSL)

Influenza

≤0.2 pg [2.0 × 10-7 mcg] (Neomycin sulfate)

 

Agriflu (Novartis)

Influenza

≤0.02 mcg (Neomycin sulfate)

 

Fluvirin (Novartis)

Influenza

≤2.5 mcg

 

Havrix (GSK)

Hep A

≤40 ng/mL (Neomycin sulfate)

 

Imovax Rabies (sp)

Rabies

<150 mcg (Neomycin Sulfate)

 

IPOL (sp)

Polio

<5 ng [.005 mcg]

 

Kinrix (GSK)

DTaP/IPV

≤0.05 ng [5.0 × 10-5 mcg]

 

MMR II (Merck)

MMR

25 mcg

 

Pediarix (GSK)

DTaP-HepB-IPV

≤0.05 ng [5.0 × 10-5 mcg]

 

Pentacel (sp)

DTaP-IPV-Hib

<4 pg [4.0 × 10-6 mcg]

 

ProQuad (Merck)

MMR+Varicella

<16 mcg

 

RabAvert (Chiron)

Rabies

< 1 mcg

 

Twinrix (GSK)

Hep AB

≤20 ng [0.02 mcg]

 

Vaqta (Merck)

Hepatitis A

<10 ppb

 

Varivax (Merck)

Varicella

trace amounts

 

Zostavax (Merck)

Varicella Zoster

trace amounts

Ovalbumin

Afluria (CSL)

Influenza

≤ 1 mcg

 

Fluarix (GSK)

Influenza

≤ 0.05 mcg

 

FluLaval (sp)

Influenza

≤1 mcg

 

Fluvirin (Novartis)

Influenza

≤1 mcg

 

RabAvert (Novartis)

Rabies

< 3 ng [0.003 mcg]

Polymyxin B

ACAM2000 (sp)

Smallpox

trace amounts

 

Afluria (CSL)

Influenza

≤0.03 pg [3.0 × 10-8 mcg]

 

Fluvirin (Novartis)

Influenza

≤3.75 mcg

 

IPOL (sp)

Polio

25 ng [0.025 mcg]

 

Kinrix (GSK)

DTaP/IPV

≤0.01 ng [1.0 × 10-5 mcg]

 

Pediarix (GSK)

DTaP-HepB-IPV

≤0.01 ng [1.0 × 10-5 mcg]

 

Pentacel (sp)

DTaP-IPV-Hib

<4 pg [4.0 × 10-6 mcg] (polymyxin B sulfate)

 Serum, Fetal Bovine

IPOL (sp)

Polio

<1 ppm

 

MMR II (Merck)

MMR

<1 ppm

 

ProQuad (Merck)

MMR+varicella

0.5 mcg

 

RotaTeq (Merck)

Rotavirus

trace amounts

 

Varivax (Merck)

Varicella

trace amounts

 

Zostavax (Merck)

Varicella Zoster

trace amounts

Sodium taurodeoxycholate

Afluria (CSL)

Influenza

<10 ppm

Streptomycin

IPOL (sp)

Polio

<200 ng [0.2 mcg]

Thimerosal

ActHIB (AP)

Hib

≤0.3 mcg

Afluria (CSL)

Influenza

24.5 mcg mercury

 

Decavac (sp)

Td

≤0.3 mcg mercury

 

DT (sp)

DT

≤0.3 mcg mercury in 1 mL vial

 

FluLaval (GSK)

Influenza

25 mcg mercury

 

Fluvirin (Novartis)

Influenza

25 mcg mercury per dose in multi-dose vial

 

Fluzone (sp)

Influenza

25 mcg mercury in multi-dose vial

 

JE-Vax (sp)

Japanese Encephalitis

0.007%

 

MENOMUNE (sp)

Meningococcal

25 mcg mercury in multi-dose diluent

 

Td Adsorbed (Aventis)

Tetanus Toxoid Adsorbed

≤0.3 mcg mercury

 

TriHIBit (sp)

Hib

trace amounts

 

Tripedia (sp)

DTaP

trace amounts; ≤0.3 mcg mercury

Yeast

Comvax (Merck)

Hib-HepB

≤1% yeast protein

 

Engerix-B (GSK)

Hep B

<5% yeast protein

 

Gardasil (Merck)

HPV

<7 mcg yeast protein/dose

 

Menveo (Novartis)

Meningococcal

"...CY medium containing yeast extracts ..."

 

Pediarix (GSK)

Hep B

≤5% yeast protein

 

Prevnar (WL)

Pneumococcal

"…and yeast extract-based medium"

 

Recombivax HB (Merck)

Hep B

≤1% yeast protein

 

Twinrix (GSK)

Hep AB

≤5% yeast protein

 

Vivotif Berna (Berna)

Typhoid

yeast extract from media

updated January 2011

 

 

This page was last updated on December 22, 2011

© 2011 Institute for Vaccine Safety