Components of Typhoid Vaccines	Excipients Table Allergens Table Components Table
Indication Induction of active immunity against typhoid fever Proprietary Name Typhim Vi Vivotif Berna Manufacturers sanofi pasteur Berna Viability Inactivated Live, attenuated Microorganism Salmonella enterica serovar typhi, S typhi Ty2 strain Salmonella typhi Ty21a Approved Ages 2 years and older  6 years and older Dose 0.5 mL  One enteric-coated capsule Route Adults - Intramuscular in Deltoid Children - Intramuscular in Deltoid or vastus lateralis Oral Dose form Liquid solution Capsule Appearance Clear, colorless Salmon/white capsule Concentration (per 0.5 mL Typhim VI or one capsule for Vivotif) Purified Vi polysaccharide, 25 mcg Salmonella typhi Ty21a, 2-6x109 colony-forming units Excipients Sodium chloride, 4.150 mg Disodium phosphate, 0.065 mg Monosodium phosphate, 0.023 mg Sterile Water, 0.5mL Polydimethylsilozane-based antifoam agents, residual Sucrose, 26–130 mg Ascorbic acid, 1–5 mg Amino acid mixture, 1.4–7 mg Lactose, 100–180 mg Magnesium stearate 3.6–4.4 mg Adjuvant None None Allergens None Lactose, 100–180 mg Yeast extract from media Preservatives Phenol, 0.25% None Media Semi-synthetic medium without animal proteins Yeast extract (consisting of casein, dextrose and galactose) Packaging Syringe without needle Vial, 20-dose Single foil blister contains 4 doses of vaccine Routine Storage 2 to 8° C (36 to 46° F) Do not freeze 2 to 8° C (36 to 46° F) Do not freeze Package Insert date December 2005 August 2006 updated January 2012
This page was last updated on January 23, 2012 © 2012 Institute for Vaccine Safety